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Ph.D. research summary in 25 slides
Li Chen Curriculum Vitae
Last update: Sep 2022
Medical Image Analysis, Machine Learning, Computer Vision
Sep. 2016 – Aug. 2021 | Ph.D. in Electrical and Computer Engineering, University of Washington |
Dissertation: Feature extraction and quantification to explore human vasculature. (PPT) (PDF)
Research assistant in Vascular Imaging Lab. Co-advised by Prof. Chun Yuan and Prof. Jenq-Neng Hwang Overall GPA: 3.89 /4.0 | |
Sep. 2012 – June 2016 | B.S. in Electrical Engineering, Fudan University |
Overall GPA: 3.6 /4.0 Ranking: 9% | |
Jan. 2015 – May. 2015 | Exchange Student in National University of Singapore |
Overall GPA: 5.0 /5.0 |
Oct. 2021 – Now | Research Scientist, Philips Research North America |
Ultrasound AI Group, Department of Precision Diagnosis and Image-Guided Therapy, Philips Research Innovation Hub Cambridge MA. Managed by Dr. Alvin Chen.
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May – Aug. 2021 | Research Intern, Genentech, Inc. |
Early Clinical Development Informatics (ECDi) group. Advised by Dr. Reza Negahdar. | |
June – Sep. 2020 | Research Intern, United Imaging Intelligence America |
Medical AI group. Advised by Dr. Shanhui Sun and Terrence Chen. |
The image processing and analysis techniques allow machines to understand the content of images and reveal important information from medical images. For example, by using object tracking method artery of interest from 3D vascular images can be automatically identified, and an artery centerline can be generated for the following up visualization and vessel analysis. Another example is image registration from two time points to observe disease development. Accurate analysis on medical images helps to identify features and patterns in addition to traditional clinical features, so that they can be utilized to identify subjects with health problems, such as identifying people with high risk of plaques and detecting health status from tongue images. Applying these features in future clinical studies might establish a new approach for further our understanding of disease mechanism and prevention.
The powerful ability of machine learning techniques, especially deep learning techniques are bringing great benefits to medical solutions. I am actively taking the role of bridging the gap between technical and medical society by learning the clinical needs and applying machine learning techniques to clinical applications. I have developed several clinically usable machine learning models to allow clinicians to easily use the advance techniques in their routine work or research. For example, I have developed an automated lumen and outer wall segmentation model using deep learning, which takes 5% of manual review time while having similar performance with expert readers. With that, we can process the whole OAI dataset within two months, a workload of 67 years of manual labeling, and thus we are able to analyze and summarize the vessel wall conditions in 3.5 million knee images. Another example is the high-risk atherosclerotic lesion detection model which is able to identify carotid artery centerlines and highlight the segments with high risk lesions, which is effective in reducing the manual review time and improve the detection sensitivity. Machine learning will definitely make tremendous contributions to the medical society in the future, and I am passionate to be involved in this exciting direction.
Modeling vascular regions shown in vascular images into a topological network (vasculature tree) is a novel image analysis method to allow quantification of artery structures and blood flow. Quantitative measurements from the vasculature tree, including artery length, volume, tortuosity and signal intensity, provide novel imaging biomarkers for various research topics, such as evaluation of artery and flow differences in a certain population of interest, and identify vascular changes between time points. A series of research have been available since the development and validation of an artery feature extraction tool (iCafe, highlighted in Editor's Pick of the MRM journal). I have developed iCafe, validated its reliability on extracting features from TOF MRA, and applied iCafe on various interesting research projects, for example, exploration of cerebral vasculature declines for elderly in a cross-sectional study. iCafe can also be applied on other imaging sequences (CTA) or vascular beds (peripheral arteries).
Philips Research North America | Oct. 2021 ~ Now |
Research Scientist. Ultrasound AI group. | Cambridge, MA |
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Vascular Imaging Lab & Information Processing Lab, University of Washington | Sep. 2016 ~ Aug. 2021 |
Research Assistant. Co-advised by Prof. Chun Yuan, Department of Radiology and Bioengineering, and Prof. Jenq-Neng Hwang, Department of Electrical and Computer Engineering | Seattle, WA |
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Genentech, Inc. | May ~ Aug. 2021 |
Research intern. Advised by Dr. Reza Negahdar, Early Clinical Development Informatics (ECDi) group. | South San Francisco, CA |
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United Imaging Intelligence America | June ~ Sep. 2020 |
Research intern. Advised by Dr. Shanhui Sun and Terrence Chen, Medical AI group | Boston, MA |
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Circuit Theory and Application Lab, Fudan University | Oct. 2013 ~ June 2016 |
Undergraduate Researcher. Advised by: Dr. Huiliang Shang, Associate Professor, Department of Electronic Engineering | Shanghai, China |
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Adaptive Networks and Control Lab (CAN), Fudan University | Mar. 2014 ~ Mar. 2015 |
Undergraduate Researcher. Advised by: Prof. Xiang Li, Professor, Department of Electronic Engineering | Shanghai, China |
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Key Laboratory of EMW information, Fudan University | Oct. 2013 ~ Nov. 2014 |
Undergraduate Researcher. Advised by: Prof. Bin Wang, Professor, Department of Electronic Engineering | Shanghai, China |
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Fudan Physic Teaching Lab, Fudan University | Sep. 2013 ~ Dec. 2013 |
Undergraduate Researcher. Advised by: Prof. Yongkang Le, Professor, Department of Physics | Shanghai, China |
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For Whole Research Experience, Link to Project Journey
[J27] Kaiyu Zhang, Zhensen Chen, Li Chen, Gador Canton, Duygu Baylam Geleri, Baocheng Chu, Yin Guo, Daniel S.Hippe, Kristi D. Pimentel, Niranjan Balu, Thomas S. Hatsukam, Chun Yuan. Alterations in cerebral distal vascular features and effect on cognition in a high cardiovascular risk population: A prospective longitudinal study. Magnetic Resonance Imaging (IF:3.13), 2023, 98 (May 2023), Pages 36-43. DOI: 10.1016/j.mri.2022.12.011
[J26] Anders Gould, Zhensen Chen, Duygu Baylam Geleri, Niranjan Balu, Li Chen, Baocheng Chu, Kristi Pimentel, Gador Canton, Thomas Hatsukami, Chun Yuan. Associations of Intracranial Vascular Features on Non-contrast Enhanced MRA with Cognitive Impairment (P15-10.001). Neurology (IF:9.901), 2022, 98 (18 Supplement).
[J25] Zhensen Chen, Anders Gould, Duygu Baylam Geleri, Niranjan Balu, Li Chen, Baocheng Chu, Kristi Pimentel, Gador Canton, Thomas S Hatsukami, Chun Yuan. Associations of intracranial artery length and branch number on non-contrast enhanced MRA with cognitive impairment in individuals with carotid atherosclerosis. Scientific Reports (IF:4.996), 2022, 2022, Pages 7456. DOI: 10.1038/s41598-022-11418-y
[J24] Jie Sun, Mahmud Mossa-Basha, Gador Canton, Niranjan Balu, Yin Guo, Li Chen, Dongxiang Xu, Daniel S Hippe, Kristi D Pimentel, Thomas S Hatsukami, Chun Yuan. Characterization of non-stenotic plaques in intracranial arteries with multi-contrast, multi-planar vessel wall image analysis. Journal of Stroke and Cerebrovascular Diseases (IF:2.136), 2022, 31 (10), Pages 106719. DOI: 10.1016/j.jstrokecerebrovasdis.2022.106719
[J23] Yin Guo, Gador Canton, Li Chen, Jie Sun, Duygu Baylam Geleri, Niranjan Balu, Dongxiang Xu, Mahmud Mossa-Basha, Thomas S. Hatsukami, Chun Yuan. Multi‐Planar, Multi‐Contrast and Multi‐Time Point Analysis Tool MOCHA for Intracranial Vessel Wall Characterization in Journal of Magnetic Resonance Imaging. Journal of Magnetic Resonance Imaging (IF:4.813), 2022, 56 (3), Pages 944-955. DOI: 10.1002/jmri.28087
[J22] Lanxin Ji, Yuhui Xiong, Le He, Li Chen, Xue Zhang, Zhensen Chen, Xuesong Li, Huilin Zhao, Manabu Shirakawa, Chun Yuan, Yu Ma. Effects of Levodopa Therapy on Cerebral Arteries and Perfusion in Parkinson’s Disease Patients. Journal of Magnetic Resonance Imaging (IF:4.8), 2021, 55 (3), Pages 943-953. DOI: 10.1002/jmri.27903
[J21] Wenjin Liu, Xiaoqin Huang, Xuebing Liu, Lulu Wang, Zhensen Chen, Dakota Ortega, Li Chen, Jie Sun, Thomas S Hatsukami, Chun Yuan, Haige Li, junwei yang. Urinary Sodium and Potassium Excretion and Cerebrovascular Health: A Multimodal Imaging Study. European Journal of Nutrition (IF:4.7), 2021, 60 (8), Pages 4555–4563. DOI: 10.1007/s00394-021-02612-1
[J20] Duygu Baylam Geleri, Hiroko Watase, Baocheng Chu, Li Chen, Huilin Zhao, Xihai Zhao, Thomas Hatsukami, and Chun Yuan. Detection of Advanced Lesions on Carotid Arteries using 3D-MERGE Magnetic Resonance Imaging as a Screening Tool. Stroke (IF:7.2), 2021, 53 (1), Pages 194–200. DOI: 10.1161/STROKEAHA.120.032505
[J19] Li Chen, Dennis W.W. Shaw, Stephen R. Dager, Neva M Corrigan, Baocheng Chu, Natalia Maria Kleinhans, Patricia Kuhl, Jenq-Neng Hwang and Chun Yuan. Quantitative Assessment of the Intracranial Vasculature of Infants and Adults using iCafe (intraCranial Artery Feature Extraction). Frontiers in Neurology (IF:2.9), 2021, 28 May 2021. DOI: 10.3389/fneur.2021.668298 (pdf)
[J18] Anders Gould, Zhensen Chen, Duygu Baylam Geleri, Niranjan Balu, Zechen Zhou, Li Chen, Baocheng Chu, Kristi Pimentel Gador Canton Thomas Hatsukami, Chun Yuan. Vessel length on SNAP MRA and TOF MRA is a potential imaging biomarker for brain blood flow. Magnetic Resonance Imaging (IF:2.1), 2021, 79 (June 2021), Pages 20-27. DOI: 10.1016/j.mri.2021.02.012
[J17] Gador Canton, Daniel Hippe, Li Chen, John Waterton, Wenjin Liu, Hiroko Watase, Niranjan Balu, Jie Sun, Thomas Hatsukami, Chun Yuan. Atherosclerotic Burden and Remodeling Patterns of the Popliteal Artery as detected in the MRI Osteoarthritis Initiative Dataset. JAHA: Journal of the American Heart Association (IF:4.67), 2021, 10 (11). DOI: 10.1161/JAHA.120.018408
[J16] Li Chen, Huilin Zhao, Hongjian Jiang, Niranjan Balu, Hiroko Watase, Duygu Baylam Geleri, Xihai Zhao, Rui Li, Jianrong Xu, Thomas S. Hatsukami, Dongxiang Xu, Jenq-Neng Hwang, Chun Yuan. Domain Adaptive and Fully Automated Carotid Artery Atherosclerotic Lesion Detection using an Artificial Intelligence Approach (LATTE) on 3D MRI. Magnetic resonance in medicine (IF:3.6), 2021, 86 (3), Pages 1662-1673. DOI: 10.1002/MRM.28794
[J15] Wenjin Liu, Zhensen Chen, Dakota Ortega, Xuebing Liu, Xiaoqin Huang, Lulu Wang, Li Chen, Jie Sun, Thomas S Hatsukami, Chun Yuan, Haige Li, Junwei Yang. Arterial Elasticity, Endothelial Function and Intracranial Vascular Health: A Multimodal MRI Study. Journal of Cerebral Blood Flow and Metabolism (IF:5.7), 2020, 41 (6), Pages 1390-1397. DOI: 10.1177/0271678X20956950
[J14] Zhensen Chen, Li Chen, Manabu Shirakawa, Wenjin Liu, Dakota Ortega, Jinmei Chen, Niranjan Balu, Theodore Trouard, Thomas Hatsukami, Wei Zhou, Chun Yuan. Intracranial vascular feature changes in time of flight MR angiography in patients undergoing carotid revascularization surgery. Magnetic Resonance Imaging (IF:2.1), 2020, 75 (January 2021), Pages 45-50. DOI: 10.1016/j.mri.2020.10.004
[J13] Wenjin Liu, Xiaoqin Huang, Xuebing Liu, Dakota Ortega, Li Chen, Zhensen Chen, Jie Sun, Lulu Wang, Thomas S. Hatsukami, Chun Yuan, Haige Li & Junwei Yang. Uncontrolled hypertension associates with subclinical cerebrovascular health globally: a multimodal imaging study. European Radiology (IF:4.1), 2020, 31 (14 September 2020), Pages 2233–2241. DOI: 10.1007/s00330-020-07218-5
[J12] Daniel Hippe, Niranjan Balu, Li Chen, Gador Canton, Wenjin Liu, Hiroko Watase, John Waterton, Thomas Hatsukami, Jenq-Neng Hwang, Chun Yuan. Confidence weighting for robust automated measurements of popliteal vessel wall MRI. Circulation: Genomic and Precision Medicine (IF:4.9), 2020, 13 (1), Pages 39-41. DOI: 10.1161/CIRCGEN.119.002870
[J11] Li Chen, Stephen R. Dager, Dennis W.W. Shaw, Neva M. Corrigan, Mahmud Mossa-Basha, Kristi D. Pimentel, Natalia M. Kleinhans, Patricia K. Kuhl, Jenq-Neng Hwang, Chun Yuan. A Novel Algorithm for Refining Cerebral Vascular Measurements in Infants and Adults. Journal of Neuroscience Methods (IF:2.8), 2020, 340 (1 July 2020), Pages 108751. DOI: 10.1016/j.jneumeth.2020.108751
[J10] Li Chen, Jie Sun, Gador Canton, Niranjan Balu, Daniel S. Hippe, Xihai Zhao, Rui Li, Thomas S. Hatsukami, Jenq-Neng Hwang, Chun Yuan. Automated Artery Localization and Vessel Wall Segmentation of Vessel Wall Images using Tracklet Refinement and Polar Conversion . IEEE Access, 2020, 8, Pages 217603-217614. DOI: 10.1109/ACCESS.2020.3040616 (pdf) (code)
[J9] Li Chen, Gador Canton, Wenjin Liu, Daniel S. Hippe, Niranjan Balu, Hiroko Watase, Thomas S. Hatsukami, John C. Waterton, Jenq-Neng Hwang, Chun Yuan. Fully automated and Robust Analysis Technique for Popliteal Artery Vessel Wall Evaluation (FRAPPE) using Neural Network Models from Standardized Knee MRI. Magnetic resonance in medicine (IF:3.6), 2020, 84, Pages 2147–2160. DOI: 10.1002/mrm.28237 (pdf)
[J8] Qiang Zhang, Zhensen Chen, Shuo Chen, Xinke Liu, Jia Ning, Yongjun Han, Li Chen, Le He, Xihai Zhao, Yuhui Xiong, Hua Guo, Chun Yuan, Rui Li, Huijun Chen. Angiographic contrast mechanism comparison between Simultaneous Non-contrast Angiography and intraPlaque hemorrhage (SNAP) sequence and Time of Flight (TOF) sequence for intracranial artery. Magnetic Resonance Imaging (IF:2.1), 2019, 66 (February 2020), Pages 199-207. DOI: 10.1016/j.mri.2019.09.001
[J7] Li Chen, Jie Sun, Daniel S Hippe, Niranjan Balu, Quan Yuan, Isabelle Yuan, Xihai Zhao, Rui Li, Le He, Thomas S. Hatsukami, Jenq-Neng Hwang, Chun Yuan. Quantitative Assessment of the Intracranial Vasculature in an Older Adult Population using iCafe (intraCranial Artery Feature Extraction). Neurobiology of Aging (IF:4.4), 2019, 79 (July 2019), Pages 59-65. DOI: 10.1016/j.neurobiolaging.2019.02.027 (pdf)
[J6] Li Chen, Mahmud Mossa-Basha, Jie Sun, Daniel S Hippe, Niranjan Balu, Quan Yuan, Kristi Pimentel, Thomas S. Hatsukami, Jenq-Neng Hwang, Chun Yuan*. Quantification of morphometry and intensity features of intracranial arteries from 3D TOF MRA using the intracranial artery feature extraction (iCafe): A reproducibility study. Magnetic Resonance Imaging (IF:2.1), 2019, 57 (April 2019), Pages 293-302. DOI: 10.1016/j.mri.2018.12.007 (pdf)
[J5] Li Chen, Mahmud Mossa‐Basha, Niranjan Balu, Gador Canton, Jie Sun, Kristi Pimentel, Thomas S Hatsukami, Jenq‐Neng Hwang, Chun Yuan. Development of a quantitative intracranial vascular features extraction tool on 3D MRA using semiautomated open‐curve active contour vessel tracing. Magnetic resonance in medicine (IF:3.9), 2018, 79 (6), Pages 3229-3238. DOI: 10.1002/mrm.26961 (Editor's pick) (pdf) (ppt)
[J4] Li Chen, Yuxi Lian, Yi Guo, Yuanyuan Wang, Thomas S Hatsukami, Kristi Pimentel, Niranjan Balu, Chun Yuan. A vascular image registration method based on network structure and circuit simulation. BMC bioinformatics (IF:2.5), 2017, 18 (1), Pages 229. DOI: 10.1186/s12859-017-1649-1 (pdf)
[J3] Miao Wang, Li Chen, Yanjun Huang, Lei Zhang, Zihao Zhang, Jie Ding, Huiliang Shang. The application characteristics of traditional Chinese medical science treatment on vertigo based on data mining Apriori algorithm. International Journal of Wireless and Mobile Computing (IF:1.2), 2015, 9 (4), Pages 349-354. DOI: 10.1504/IJWMC.2015.074041
[J2] Miao Wang, Li Chen, Qing Li, Dongyi Wang, Yiqin Liu, Yi Zhang, Shoulan Bing, Huiliang Shang. An adaptive computer-aided tongue diagnosis method using colour-calibration preprocessing and multiple feature synthesis based on Android platform. International Journal of Wireless and Mobile Computing (IF:1.2), 2015, 9 (3), Pages 240-249. DOI: 10.1504/IJWMC.2015.073107
[J1] Li Chen, Dongyi Wang. An improved acquaintance immunization strategy for complex network. Journal of theoretical biology (IF:2.1), 2015, (385), Pages 58-65. DOI: 10.1016/j.jtbi.2015.07.037 (pdf) (ppt)
[C11] Gary Y. Li, Li Chen, Mohsen Zahiri, Naveen Balaraju, Shubham Patil, Courosh Mehanian, Cynthia Gregory, Kenton Gregory, Balasundar Raju, Jochen Kruecker, Alvin Chen. Weakly Semi-supervised Detector-based Video Classification with Temporal Constraints for Lung Ultrasound. ICCV 2023 Workshop on Computer Vision for Automated Medical Diagnosis, 2023, Paris Convention Center in Paris, France. (October 2-3, 2023).
[C10] Jiahong Ouyang, Li Chen*, Gary Y. Li, Naveen Balaraju, Shubham Patil, Courosh Mehanian, Sourabh Kulhare, Rachel Millin, Kenton W. Gregory, Cynthia R. Gregory, Meihua Zhu, David O. Kessler, Laurie Malia, Almaz Dessie, Joni Rabiner, Di Coneybeare, Bo Shopsin, Andrew Hersh, Cristian Madar, Jeffrey Shupp, Laura S. Johnson, Jacob Avila, Kristin Dwyer, Peter Weimersheimer, Balasundar Raju, Jochen Kruecker, and Alvin Chen. Weakly Semi-Supervised Detection in Lung Ultrasound Videos. The 28th biennial international conference on Information Processing in Medical Imaging, 2023, San Carlos de Bariloche, Argentina (18 to 23 June 2023).
[C9] Li Chen*, Jonathan Rubin*†, Jiahong Ouyang, Naveen Balaraju, Shubham Patil, Courosh Mehanian, Sourabh Kulhare, Rachel Millin, Kenton W. Gregory, Cynthia R. Gregory, Meihua Zhu, David O. Kessler, Laurie Malia, Almaz Dessie, Joni Rabiner, Di Coneybeare, Bo Shopsin, Andrew Hersh, Cristian Madar, Jeffrey Shupp, Laura S. Johnson, Jacob Avila, Kristin Dwyer, Peter Weimersheimer, Balasundar Raju, Jochen Kruecker, Alvin Chen. Contrastive self-supervised learning for spatio-temporal analysis of lung ultrasound videos. IEEE International Symposium on Biomedical Imaging (ISBI) , 2023, Cartagena, Colombia (April 18 - 21, 2023).
[C8] Luojie Huang, Yikang Liu, Li Chen, Eric Z. Chen, Xiao Chen, Shanhui Sun. Robust Landmark-based Stent Tracking in X-ray Fluoroscopy. European Conference on Computer Vision, 2022, Tel Aviv, Israel (October 23-27).
[C7] Li Chen, Wenjin Liu, Niranjan Balu, Mahmud Mossa-Basha, Thomas S. Hatsukami, Jenq-Neng Hwang, Chun Yuan. Deep Open Snake Tracker for Vessel Tracing. MICCAI 2021, the 24th International Conference on Medical Image Computing and Computer Assisted Intervention, 2021, Strasbourg, France (September 27th to October 1st). DOI: 10.1007/978-3-030-87231-1_56
[C6] Li Chen, Thomas Hatsukami, Jenq-Neng Hwang, Chun Yuan. Automated Intracranial Artery Labeling using a Graph Neural Network and Hierarchical Refinement. MICCAI 2020, the 23rd International Conference on Medical Image Computing and Computer Assisted Intervention, 2020, Lima, Peru (October 4 - 8, 2020). DOI: 10.1007/978-3-030-59725-2_8 (pdf) (ppt) (code)
[C5] Hongjian Jiang, Li Chen, Dongxiang Xu, Huilin Zhao, Hiroko Watase, Xihai Zhao, Rui Li, Chun Yuan. A Target-Oriented and Multi-Patch Based Framework for Image Quality Assessment on Carotid Artery MRI. Medical Imaging 2020: Image Processing. SPIE, 2020, Marriott Marquis Houston, Houston, Texas, United States (February 15 - 20). DOI: 10.1117/12.2549473
[C4] Li Chen, Gaoang Wang, Niranjan Balu, Mahmud Mossa-Basha, Xihai Zhao, Rui Li, LeHe, Thomas S. Hatsukami, Jenq-Neng Hwang, Chun Yuan. Simultaneous Intracranial Artery Tracing and Segmentation from Magnetic Resonance Angiography by Joint Optimization from Multiplanar Reformation. Machine Learning and Medical Engineering for Cardiovascular Health and Intravascular Imaging and Computer Assisted Stenting, First International Workshop, MLMECH 2019, and 8th Joint International Workshop, CVII-STENT 2019, Held in Conjunction with MICCAI, 2019, Shenzhen, China (October 13), Pages 201-209. DOI: 10.1007/978-3-030-33327-0 (pdf) (ppt)
[C3] Li Chen, Yanjun Xie, Jie Sun, Niranjan Balu, Mahmud Mossa-Basha, Kristi Pimentel, Thomas S Hatsukami, Jenq-Neng Hwang, Chun Yuan. 3D intracranial artery segmentation using a convolutional autoencoder. 2017 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), 2017, Kansas City, MO, USA (November 13 - 16). DOI: 10.1109/BIBM.2017.8217741 (pdf) (ppt)
[C2] Miao Wang, Jiayun Li, Li Chen, Yanjun Huang, Qiang Zhou, Lijuan Che, Huiliang Shang. The Study of the Compatibility Rules of Traditional Chinese Medicine Based on Apriori and HMETIS Hypergraph Partitioning Algorithm. VLDB Workshop on Big Graphs Online Querying, 2015, Waikoloa, HI, USA (August 31 – September 4), Pages 16-31. DOI: 10.1007/978-3-319-41576-5_2 (pdf)
[C1] Li Chen, Dongyi Wang, Yiqin Liu, Xiaohang Gao, Huiliang Shang. A novel automatic tongue image segmentation algorithm: Color enhancement method based on L* a* b* color space. Bioinformatics and Biomedicine (BIBM), 2015 IEEE International Conference on, 2015, Washington D.C., USA ( November 9-12), Pages 990-993. DOI: 10.1109/BIBM.2015.7359818 (pdf) (ppt)
[P3] Li Chen, Wenjin Liu, Gador Canton, Niranjan Balu, Thomas Hatsukami, John C. Waterton, Jenq-Neng Hwang, Chun Yuan. Visualizing and utilizing the latent features of MR vessel wall images using weakly supervised deep learning analysis workflow. 2020 Annual Meeting of International Society for Magnetic Resonance in Medicine (ISMRM), 2020, ICC Sydney, Sydney, Australia (17-20 April 2020). (Magna Cum Laude Merit Award) (pdf) (ppt)
[P2] Li Chen, Huilin Zhao, Niranjan Balu, Xihai Zhao, Rui Li, Jenq-Neng Hwang, Chun Yuan. Carotid Artery Localization and Lesion Detection on 3D-MERGE MRI through Online Learning.. Society for Magnetic Resonance Angiography 30th Annual International Conference, 2018, University of Glasgow, Glasgow, Scotland (August 29-31).
[P1] Li Chen, Jie Sun, Niranjan Balu, Thomas S. Hatsukami, Mahmud MossaBasha, Kristi D. Pimentel, Jenq-Neng Hwang, Chun Yuan. Automated detection and labeling of the intracranial arterial tree in routine MR angiography: A machine learning approach enhanced with structural saliency. Radiological Society of North America's 103rd Scientific Assembly and Annual Meeting, 2017, McCormick Place, Chicago, Illinois (November 26 - December 1).
[T4] Li Chen. Fully automated and Robust Analysis Technique for Popliteal Artery Vessel Wall Evaluation (FRAPPE) using Neural Network Models from Standardized Knee MRI. Imaging Elevated: Utah Symposium for Emerging Investigators , 2020, October 7-9, 2020 • Salt Lake City, UT.
[T3] Li Chen. Image analysis and AI/deep learning applications on vascular research. Invited talk, 2019, Renji Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China (October 9).
[T2] Li Chen. Looking into intracranial artery map with big data and machine learning. Intelligent Medical Imaging Symposium, 2018, Tsinghua University, Beijing, China (July 1).
[T1] Li Chen. Development of a Quantitative Intracranial Vascular Features Extraction Tool on 3D MRA Using Semi-automated Open-Curve Active Contour Vessel Tracing. UW-Philips MRX, 2017, University of Washington (September 22).
[X2] Li Chen, Jie Sun, Gador Canton, Niranjan Balu, Xihai Zhao, Rui Li, Thomas S. Hatsukami, Jenq-Neng Hwang, Chun Yuan. Automated Artery Localization and Vessel Wall Segmentation of Magnetic Resonance Vessel Wall Images using Tracklet Refinement and Polar Conversion. arXiv preprint, 2019, (arXiv: 1909.02087). (pdf)
[X1] Li Chen, Yanjun Xie, Jie Sun, Niranjan Balu, Mahmud Mossa-Basha, Kristi Pimentel, Thomas S Hatsukami, Jenq-Neng Hwang, Chun Yuan. Y-net: 3D intracranial artery segmentation using a convolutional autoencoder. arXiv preprint, 2017, (arXiv: 1712.07194). (pdf)
[A18] Nhat Hoang, Henry Wang, Sahin Bogachan, Muhammad Waqas Khan, Abrar Faiyaz, Meera Singh, Jinjiang Pang, Shumin Wang, Li Chen, Chun Yuan, Jianhui Zhong, Hongmei Yang, Md Nasir Uddin, and Giovanni Schifitto. Effects of HIV-associated chronic inflammation on intracranial vessels using semi-automatic segmentation of MRA cerebrovascular features. 2023 Annual Meeting of International Society for Magnetic Resonance in Medicine (ISMRM), 2023, Toronto, Canada (3-8 June).
[A17] Alvin Chen, Shubham Patil, Mohsen Zahiri, Li Chen, Bryson Hicks, Nikolai Schnittke, Meihua Zhu, Jeffrey Shupp, Kenton Gregory, Jochen Kruecker, Balasundar Raju. Artificial Intelligence Model to Identify Pleural Line Abnormalities in Lung Ultrasound. American College of Emergency Physicians 2023 Scientific Assembly, 2023, Philadelphia (Oct. 9-12).
[A16] Yin Guo, Li Chen, Dongxiang Xu, Rui Li, Xihai Zhao, Thomas S. Hatsukami, Chun Yuan. AI-based Computer-Aided System for Cardiovascular Disease Evaluation (AI-CASCADE) forcarotid tissue quantification. 2021 Annual Meeting of International Society for Magnetic Resonance in Medicine (ISMRM), 2021, Vancouver, Canada (15-20 May).
[A15] Kaiyue Tao, Li Chen, Niranjan Balu, Gador Canton, Wenjin Liu, Thomas S. Hatsukami, Chun Yuan. Exploring feature space of MR vessel images with limited data annotations through metriclearning and episodic training. 2021 Annual Meeting of International Society for Magnetic Resonance in Medicine (ISMRM), 2021, Vancouver, Canada (15-20 May).
[A14] Niranjan Balu, Wenjin Liu, Zhensen Chen, Anders Gould, Dan S Hippe, Li Chen, Binbin Sui, Mi Shen, Peiyi Gao, Thomas S Hatsukami, Chun Yuan. Reproducibility of quantitative measures of intracranial arterial geometry: dependence onsequence and scanner platform diferences. 2021 Annual Meeting of International Society for Magnetic Resonance in Medicine (ISMRM), 2021, Vancouver, Canada (15-20 May).
[A13] Zhensen Chen, Li Chen, Manabu Shirakawa, Wenjin Liu, Dakota Ortega, Jinmei Chen, Niranjan Balu, Theodore Trouard, Thomas S Hatsukami, Wei Zhou, and Chun Yuan. Flow measurement with time of flight (TOF) in patients undergoing carotid revascularization: A comparison with arterial spin labeling (ASL). 2020 Annual Meeting of International Society for Magnetic Resonance in Medicine (ISMRM), 2020, ICC Sydney, Sydney, Australia (17-20 April 2020).
[A12] Yuhui Xiong, Lanxin Ji, Le He, Li Chen, Xue Zhang, Zhensen Chen, Xuesong Li, Huilin Zhao, Manabu Shirakawa, Chun Yuan, Yu Ma, and Hua Guo. Effects of Levodopa Therapy on Cerebral Arteries and Brain Tissue Perfusion in Parkinson’s Disease Patients. 2020 Annual Meeting of International Society for Magnetic Resonance in Medicine (ISMRM), 2020, ICC Sydney, Sydney, Australia (17-20 April 2020).
[A11] Gador Canton, Hiroko Watase, Josh Liu, Li Chen, Yin Guo, Yongjun Wang, Chun Yuan. Multiplanar reconstruction of intracranial arteries: luminal morphological characterization of atherosclerosis. 2020 Annual Meeting of International Society for Magnetic Resonance in Medicine (ISMRM), 2020, ICC Sydney, Sydney, Australia (17-20 April 2020).
[A10] Ke Han, Li Chen, Duygu Baylam Geleri, Mahmud Mossa-basha, Thomas Hatsukami, Chun Yuan. Deep-learning based Significant Stenosis detection from Multiplanar reformatted Images of traced Intracranial arteries. American Society of Neuroradiology 58th Annual Meeting, 2020, Las Vegas (May 30 – June 4). (pdf)
[A9] Li Chen, Duygu Baylam Geleri, Jie Sun, Hiroko Watase, Jiarui Cai, Yin Guo, Niranjan Balu, Dongxiang Xu, Thomas Hatsukami, Yongjun Wang, Jenq-Neng Hwang, Chun Yuan. Multi-planar, multi-contrast and multi-timepoint analysis tool (MOCHA) for intracranial vessel wall imaging review. 2020 Annual Meeting of International Society for Magnetic Resonance in Medicine (ISMRM), 2020, ICC Sydney, Sydney, Australia (17-20 April 2020). (pdf) (ppt)
[A8] Niranjan Balu, Li Chen, Thoetphum Benyakorn, Daniel S Hippe, Henrik Haraldsson, Warren Gasper, David Saloner, Chun Yuan, Thomas Hatsukami. Quantitative measurements of decreased arterial collateralization and branching in peripheral artery disease. 2019 Annual Meeting of International Society for Magnetic Resonance in Medicine (ISMRM), 2019, Palais des congrès de Montréal, Montréal, QC, Canada (May 11-16). (pdf)
[A7] Manabu Shirakawa, Li Chen, Niranjan Balu, Wenjin Liu, Dakota Ortega, Jinmei Chen, Theodore Trouard, Diane Bock, Wei Zhou, Chun Yuan, Thomas S Hatsukami. Quantitative assessment of cerebrovascular structure after carotid revascularization using intraCranial Artery Feature Extraction (iCafe) Technique. 2019 Annual Meeting of International Society for Magnetic Resonance in Medicine (ISMRM), 2019, Palais des congrès de Montréal, Montréal, QC, Canada (May 11-16). (pdf)
[A6] Li Chen, Thoetphum Benyakorn, Gador Canton, Niranjan Balu, Thomas S Hatsukami, Jenq-Neng Hwang, Chun Yuan. Development of a Quantitative Assessment tool for Peripheral Artery Feature Extraction (pCafe). 2019 Annual Meeting of International Society for Magnetic Resonance in Medicine (ISMRM), 2019, Palais des congrès de Montréal, Montréal, QC, Canada (May 11-16). (pdf)
[A5] Li Chen, Thomas Grabowski, Eric B Larson, Paul Crane, Thomas S Hatsukami, Jenq-Neng Hwang, Chun Yuan, Niranjan Balu. Quantitative Intracranial Vasculature Assessment to detect dementia using the intraCranial Artery Feature Extraction (iCafe) Technique. 2019 Annual Meeting of International Society for Magnetic Resonance in Medicine (ISMRM), 2019, Palais des congrès de Montréal, Montréal, QC, Canada (May 11-16). (Magna Cum Laude Merit Award) (pdf)
[A4] Li Chen, Huilin Zhao, Niranjan Balu, Xihai Zhao, Rui Li, Jianrong Xu, Thomas S Hatsukami, Jenq-Neng Hwang, Chun Yuan. Carotid Artery Localization and Lesion Classification on 3D-MERGE MRI using Neural Network and Object Tracking methods. 2019 Annual Meeting of International Society for Magnetic Resonance in Medicine (ISMRM), 2019, Palais des congrès de Montréal, Montréal, QC, Canada (May 11-16). (pdf) (ppt)
[A3] Li Chen, Jie Sun, Wei Zhang, Thomas S Hatsukami, Jianrong Xu, Jenq-Neng Hwang, Chun Yuan. Automatic Segmentation of Carotid Vessel Wall Using Convolutional Neural Network. 2018 Annual Meeting of International Society for Magnetic Resonance in Medicine (ISMRM), 2018, Paris Expo Porte de Versailles, Paris, France (June 16-21). (pdf)
[A2] Li Chen, Quan Yuan, Niranjan Balu, Isabelle Yuan, Daniel S Hippe, Jie Sun, Xihai Zhao, Rui Li, Le He, Jenq-Neng Hwang, Chun Yuan. Quantitative Assessment of the Intracranial Vasculature of an Elderly Population using the intraCranial Artery Feature Extraction (iCafe) Technique. 2018 Annual Meeting of International Society for Magnetic Resonance in Medicine (ISMRM), 2018, Paris Expo Porte de Versailles, Paris, France (June 16-21).
[A1] Li Chen, Mahmud Mossa-Basha, Daniel S Hippe, Jie Sun, Niranjan Balu, Kristi D. Pimentel, Thomas S Hatsukami, Jenq-Neng Hwang, Chun Yuan. Quantification of Morphometry and Intensity Features of Intracranial Arteries from 3D TOF MRA: A Reproducibility Study. 2018 Annual Meeting of International Society for Magnetic Resonance in Medicine (ISMRM), 2018, Paris Expo Porte de Versailles, Paris, France (June 16-21).
Journal Reviewer | IEEE Transactions on Medical Imaging, Journal of Biomedical and Health Informatics, Computers in Biology and Medicine, IEEE Access, Artificial Intelligence in Medicine, Medical & Biological Engineering & Computing, The International Journal of Cardiovascular Imaging, Stroke and Vascular Neurology, American Journal of Neuroradiology, Magnetic Resonance Imaging, Electronics and Telecommunications Research Institute (ETRI) Journal, PLOS ONE, International Journal of Modern Physics B. |
Conference Reviewer | the International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI), The AICity 2020 CVPR Workshop. |
Challenge Organizer | Carotid Artery Vessel Wall Segmentation Challenge. (Endorsed by SMRA 2021 and MICCAI 2021) |
2007-2009 | Shanghai AVR single chip programming contest (First prize in all three years) |
2009, 2011 | "INTEL" Innovation Contest in Shanghai |
2009 | Future Engineering Contest in Shanghai |
2009-2015 | Six consecutive years of Shu Ping Scholarship(top 3%) |
2012 | Fudan University Excellent Freshman Scholarship(top 5%) |
2013-2014 | Two consecutive years of Fudan university scholarship(top 15%) |
2015 | Mathematical Contest in Modeling 2015 (Meritorious Winner, top 10%) |
2018 | GSFEI Travel Funding, University of Washington |
2018 | Travel Stipend Awards, SMRA |
2018 | Outstanding Research Award, OCSMRM |
2018, 2019, 2020 | ISMRM Annual Meeting & Exhibition Stipend |
2019, 2020 | Magna Cum Laude Merit Award, ISMRM |
2019 | Winner for the AHA-AWS award at the 2019 American Heart Association Scientific Meeting |
Professor — Department of Radiology and Bioengineering, University of Washington,
From 2016.9 — 2021.8
Researches on Magnetic Resonance Imaging, Vulnerable Plaque/Vessel Wall Imaging and Analysis, Cardiovascular Disease Analysis and Investigation, Vessel Imaging of Vascular Cognitive Impairment and Dementia, MRI Sequence Development and Image Reconstruction, Vessel Image Processing With AI, Machine Learning, and Deep Learning.
Email: cyuan@uw.edu
Experience with me:
Course: MRI & ULTRASOUND
PhD thesis co-chair.
Professor — Department of Electrical & Computer Engineering University of Washington,
From 2016.9 — 2021.8
Researches on Image/video signal processing, Multimedia network and QoS, Statistical pattern recognition.
Email: hwang@uw.edu
Experience with me:
PhD thesis co-chair.
Accosiate Professor — Department of Electronic Engineering Fudan University,
From 2013.10 — 2016.6
Researches on image processing, Biomedical topics, Traditional Chinese medicine, Robotic, Computer vision, visible light communication, Circuit theory.
Email: shanghl@fudan.edu.cn
Experience with me:
Course: Circuit Theory
Four papers about Biomedical Image processing
LED position car etc.
Professor — Department of Electronic Engineering, Fudan University
From 2013.10 — 2014.11
Researches on image processing, signal, pattern recongnition, intelligent information proessing and brain science
Email: wangbin@fudan.edu.cn
Experience with me:
Course: Probability
The FDUROP project about image processing
Professor — Department of Electronic Engineering, Fudan University
From 2014.3 — 2015.3
Researches on complex network and multi-agent systems.
Email: lix@fudan.edu.cn
Experience with me:
Course: Introduction to Network Science
Paper about immunization network
Professor — Department of Electronic Engineering , Fudan University,
From 2015.8 — 2016.6
Researches on Medical image and signal processing, Medical ultrasonics.
Email: guoyi@fudan.edu.cn
Experience with me:
Course: Medical Imaging
Capstone research advisor
One paper on vascualr registration
Professor — Department of Electronic Engineering , Fudan University,
From 2015.8 — 2016.6
Researches on Medical image and signal processing, Medical ultrasonics.
Email: yywang@fudan.edu.cn
Experience with me:
Course: Signal and System
Final year project research group advisor
2012-2013 | Volunteer teaching in Shanghai Sunflower Weekend School, English Junior class. |
2012-2014 | Fudan Student Union, Department of Information. Technical director in 2014. |
2014.7 | Volunteer teaching in Yunnan. Lecturer in Paper cutting and Handwork (Build a gravity toy car) |
2014-2015 | Technical group of Shu Ping Scholarship Foundation. Developed online scholarship application system. |
2017-2018 | Trainee Member, Radiological Society of North America (RSNA) |
2015-2021 | IEEE student member. |
2017-2021 | Trainee Member, International Society for Magnetic Resonance in Medicine (ISMRM). |
2019-2020 | Student member, American Heart Association |
2019-2021 | Student member, Society for Medical Image Computing and Computer Assisted Intervention. |