Multi-planar , multi-contrast and multi-timepoint analysis tool ( MOCHA ) for intracranial vessel wall imaging review
Li Chen , Duygu Baylam Geleri , Jie Sun , Hiroko Watase , Jiarui Cai , Yin Guo , Niranjan Balu , Dongxiang Xu , Thomas Hatsukami , Yongjun Wang , Jenq-Neng Hwang , Chun Yuan
University of Washington, Seattle, WA, United States, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
A visualization technique (MOCHA) was developed to facilitate intracranial artery review using 3D Magnetic Resonance vessel wall imaging. Multiple intracranial MR scans, either from multiple contrasts or timepoints, are registered, then the artery of interest is traced and straightened using multiplanar reformation. Scans of 15 subjects with intracranial atherosclerosis were reviewed using MOCHA by a novice reader, with the traditional review method as comparison. The results showed higher sensitivity for plaque identification and higher accuracy for quantifying plaque features with MOCHA. MOCHA is promising for artery reviews using multiple scans, such as identifying plaque components and monitoring vessel wall thickening.